| Date | Location | Result | |
| Nov 18, 2016 | Nashville, Tenn. | Lipscomb 3, USC Upstate 0 (25-19,25-15,25-18) | Box score |
| Nov 17, 2016 | Nashville, Tenn. | USC Upstate 3, North Florida 1 (25-21,25-23,21-25,25-22) | Box score |
| Nov 13, 2016 | Spartanburg, S.C. | USC Upstate 3, Stetson 0 (25-16,25-16,25-17) | Box score |
| Nov 11, 2016 | Spartanburg, S.C. | FGCU 3, USC Upstate 2 (25-15,19-25,25-12,21-25,15-7) | Box score |
| Nov 05, 2016 | Jacksonville, Fla. | USC Upstate 3, North Florida 0 (26-24,25-17,25-22) | Box score |
| Nov 04, 2016 | Jacksonville, Fla. | Jacksonville 3, USC Upstate 1 (28-26,19-25,25-22,25-21) | Box score |
| Oct 30, 2016 | Spartanburg, S.C. | Kennesaw State 3, USC Upstate 2 (25-19,16-25,25-18,23-25,15-8) | Box score |
| Oct 28, 2016 | Spartanburg, S.C. | Lipscomb 3, USC Upstate 2 (25-27,22-25,25-19,25-17,15-8) | Box score |
| Oct 22, 2016 | Newark, NJ | NJIT 3, USC Upstate 1 (25-21,24-26,25-17,25-16) | Box score |
| Oct 15, 2016 | Nashville, Tenn. | Lipscomb 3, USC Upstate 1 (25-22,21-25,25-15,25-16) | Box score |
| Oct 14, 2016 | Kennesaw, Ga. | Kennesaw State 3, USC Upstate 0 (25-21,25-16,25-16) | Box score |
| Oct 09, 2016 | Spartanburg, S.C. | USC Upstate 3, Jacksonville 0 (25-23,26-24,25-16) | Box score |
| Oct 07, 2016 | Spartanburg, S.C. | North Florida 3, USC Upstate 0 (25-11,25-16,25-22) | Box score |
| Oct 1, 2016 | Fort Myers, Fla. | FGCU 3, USC Upstate 0 (25-15,25-22,25-13) | Box score |
| Sep 30, 2016 | DeLand, Fla. | USC Upstate 3, Stetson 2 (19-25,25-20,22-25,25-12,15-9) | Box score |
| Sep 27, 2016 | Spartanburg, S.C. | USC Upstate 3, Presbyterian College 2 (25-22,20-25,24-26,25-18,15-12) | Box score |
| Sep 24, 2016 | Spartanburg, S.C. | USC Upstate 3, NJIT 2 (28-30,25-22,22-25,25-15,15-13) | Box score |
| Sep 20, 2016 | Spartanburg, SC | USC Upstate 3, Wofford 2 (25-22,18-25,24-26,29-27,15-12) | Box score |
| Sep 17, 2016 | Macon, Ga. | Mercer 3, USC Upstate 1 (25-19,16-25,25-21,25-20) | Box score |
| Sep 16, 2016 | Macon, Ga. | USC Upstate 3, Fairleigh Dickinson 1 (21-25,25-22,25-22,26-24) | Box score |
| Sep 16, 2016 | Macon, Ga. | Towson 3, USC Upstate 2 (24-26,20-25,25-19,25-15,15-13) | Box score |
| Sep 13, 2016 | Spartanburg, S.C. | USC Upstate 3, Charlotte 2 (23-25,16-25,26-24,25-17,15-12) | Box score |
| Sep 10, 2016 | Davidson, N.C. | Furman 3, USC Upstate 0 (25-18,25-21,25-21) | Box score |
| Sep 10, 2016 | Davidson, N.C. | USC Upstate 3, Davidson 1 (25-27,25-21,25-21,25-23) | Box score |
| Sep 09, 2016 | Davidson, N.C. | USC Upstate 3, Liberty 2 (25-22,20-25,24-26,25-20,15-11) | Box score |
| Sep 06, 2016 | Spartanburg, S.C. | USC Upstate 3, Limestone 0 (25-15,25-11,25-21) | Box score |
| Sep 03, 2016 | Lynchburg, Va. | USC Upstate 3, Hampton 0 (25-20,25-21,25-23) | Box score |
| Sep 03, 2016 | Lynchburg, Va. | ETSU 3, USC Upstate 1 (21-25,25-22,25-19,25-15) | Box score |
| Sep 02, 2016 | Lynchburg, Va. | Liberty 3, USC Upstate 0 (25-17,25-19,25-16) | Box score |
| Aug 30, 2016 | Spartanburg, S.C. | Gardner-Webb 3, USC Upstate 2 (25-22,19-25,25-18,19-25,15-13) | Box score |
| Aug 27, 2016 | Johnson City, Tenn. | ETSU 3, USC Upstate 0 (25-21,25-15,25-20) | Box score |
| Aug 27, 2016 | Johnson City, Tenn. | Austin Peay State 3, USC Upstate 2 (25-22,22-25,20-25,25-19,15-10) | Box score |
| Aug 26, 2016 | Johnson City, Tenn. | Troy 3, USC Upstate 2 (14-25,18-25,25-14,25-16,15-7) | Box score |